• Professor of Medicine, Tufts University School of Medicine
• Medical Director, Case Management Medical Director, Clinical Informatics

• Critical Care Anesthesiology Fellowship
  Massachusetts General Hospital
  Boston, MA
• Internal Medicine Residency
  The Cleveland Clinic Foundation
  Cleveland, OH
• Anesthesiology Residency
  Massachusetts General Hospital
  Boston, MA

• ICU Severity-of-Illness Scoring (APACHE, MPM, SAPS, Cardiac Scores) Sepsis, Septic Shock, and Pharmacotherapy of Shock States ARDS and Mechanical Ventilation including High Frequency Oscillation Sedation and Neuromuscular Blockade Ethics and End-of-Life Decision-Making Simulation in Critical Care Education

• Critical Care Practice Committee (co-chair) Medical Staff Health Committee Intellectual Property Committee Adult Ethics Subcommittee Board of Directors, Baystate Medical Educational and Research Foundation Society of Critical Care Billing and Coding Oversight Committee Project IMPACT Research Committee

SELECTED

• Rapoport J, Teres D, Steingrub JS, Higgins TL, McGee WT, Lemeshow S:  Patient characteristics and ICU organizational factors that influence frequency of pulmonary artery catheterization.  JAMA 2000;283:2559-2567.

• Teres D, Higgins TL:  What if your hospital informatics department could provide a severity adjuster?  Crit Care Med 2000;28:3570-3571.

• Higgins TL, Murray M, Kett DH, Fulda G, Kramer KM, Gelmont D, Dedhia HV, Levy H, Teres D, Zaloga GP, Ko H, Thompson KA:  Trace element homeostasis during continuous sedation with propofol containing EDTA versus other sedatives in critically ill patients.  Intensive Care Med 2000;26:S413-S421.

• Higgins TL:  Daily versus admission mortality estimates:  Is admission severity yesterday’s news?”  Crit Care Med 2001;29:208-210.

• Higgins, TL:  Nosocomial pneumonia.  Clin Inten Care 2001;12(3):115-126.

• Higgins TL, Steingrub JS:  Advances in the therapy of sepsis.  Today’s Therapeutic Trends. 2002; 20(2): 113-133.

• Higgins TL, McGee, WT, Steingrub JS, Rapoport J, Teres D, Lemeshow S:  Early Indicators of Prolonged ICU Stay:  Impact of illness severity, physician staffing, and pre-intensive care unit length of stay.  Crit Care Med 2003;31:45-51.

• Nathanson BH, Higgins TL, Giglio RJ, Munshi IA, Steingrub, JS:  An exploratory study using data envelopment analysis to assess neurotrauma patients in the intensive care unit.  Health Care Management Science 2003;6:43-55.

• Steingrub JS, Tidswell MA, Higgins, TL:  Hemodynamic consequences of heart-lung interactions.  J Inten Care Med 2003;18(2):92-99.

• Abraham E, Reinhart K, Opal S et al for the OPTIMIST Trial Study Group (Higgins TL):  Efficacy and safety of Tifacogin (recombinant tissue factor pathway inhibitor) in severe sepsis.  A randomized controlled trial.  JAMA 2003;290:238-247.

• Higgins TL, Jodka PG, Farid A:  Pharmacologic approaches to sedation, pain relief and neuromuscular blockade in the intensive care unit.  Part I.  Sedation.  Clin Inten Care 2003;14:1-12.

• Mailloux P and Higgins TL:  Right atrial thrombus leading to altered mental status.  J Cardiothor Vasc Anes.  J Thor CV Anesth 2003;17(4):509-511.

• Higgins TL, Jodka PG, Farid A:  Pharmacologic approaches to sedation, pain relief and neuromuscular blockade in the intensive care unit.  Part II.  Pain Relief.  Clin Inten Care 2003;14:91-98.

• Higgins TL, Jodka PG, Farid A:  Pharmacologic approaches to sedation, pain relief and neuromuscular blockade in the intensive care unit.  Part III.  Neuromuscular blockade.  Clin Inten Care 2004;15(1):1-5.

• Corwin HL, Gettinger A, Pearl RG, CRIT Study (Higgins TL) et al:  The CRIT Study:  Anemia and blood transfusion in the critically ill—Current clinical practice in the United States.  Crit Care Med 2004;32(1):39-52.

• Giuliano KK and Higgins TL:  New-Generation Pulse Oximetry in the Care of Critically Ill Patients.  Am J Crit Care 2005;14:1-13.

• Higgins TL, Steingrub JS, Tidswell MA, Tereso G, McGee WT:  Drotrecogin alfa (activated) in sepsis:  Initial experience with patient selection, cost and clinical outcomes.  J Inten Care Med 2005;20:339-345.

• Moreno RP, Metnitz PGH, Almeida E, et al [SAPS 3 Investigators – Higgins TL]:  SAPS 3—From evaluation of the patient to evaluation of the intensive care unit.  Part 2:  Development of a prognostic model of hospital mortality at ICU admission.  Intensive Care Med 2005;31:1345-1355.

• Higgins TL, Teres D, Copes WS, Nathanson B, Stark M, Kramer A:  Assessing contemporary intensive care unit outcome:  An updated Mortality Probability Admission Model (MPM0-III).  Crit Care Med 2007;35:827-835.

• Nathanson B, Higgins TL, Teres D, Copes W, Kramer A, Stark M:  A revised method to assess ICU clinical performance and resource utilization.  Crit Care Med, 2007.

• Higgins TL:  Quantifying risk and benchmarking performance in the adult intensive care unit.  Journal of Intensive Care Medicine, 2007.

• Student Reviews of ICU Rotation:  http://www.scutwork.com/cgi-bin/links/review.cgi?ID=3819
• Editor; Clinical Intensive Care  http://www.tandf.co.uk/journals/authors/tcicauth.asp